Failure of etanercept and methotrexate in combination to surpass etanercept alone in psoriatic arthritis (PsA) - what about the joint counts?
We read with interest, the article on 'Etanercept and Methotrexate as Monotherapy or in Combination for Psoriatic Arthritis: Primary Results From a Randomized, Controlled Phase 3 Trial' by Philip J. Mease et al.  The failure of the combination group to better outcomes than etanercept monotherapy was a big surprise. Certain clarifications may help us understand the outcome, specifically with regard to key components of composite scores. This article is protected by copyright. All rights reserved.