Circulating T regulatory cells in patients with psoriasis with and without atherosclerosis: A pilot comparative study before and after photochemotherapy

Evidence is accumulating proving the role of T regulatory cells (Tregs) in both psoriasis and atherosclerosis pathogenesis and treatment. Psoralen-ultraviolet A (PUVA) remains a standard line of therapy for psoriasis, particularly darker phototypes, whenever the risk-benefit ratio is waived carefully. Despite the well-known therapeutic effect of UV phototherapy on psoriasis cutaneous lesions, it is still unclear if its immunomodulatory function can positively impact cardiac comorbidities in patients with psoriasis, such as atherosclerosis.

as reported in: Photodermatol Photoimmunol Photomed. 2021 May 5 [Epub ahead of print]